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Our group is interested in understanding the molecular control of actin driven processes. How does the actin cytoskeleton control changes in cell shape and cell motility in a living organism? We use Drosophila as a model system that allows combining genetics, live-imaging analyses with cell biological and biochemical approaches to identify and characterize regulatory components and signals controlling actin dynamics during development.

 

Coupling actin and membrane dynamics in planar cell polarity of the wing epithelium

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Spinning disc microscopy video. Outgrowth of prehairs (marked by Actin-EGFP) from a wing of a wild type pupa (32 APF).