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Our group is interested in understanding the molecular control of actin driven processes. How does the actin cytoskeleton control changes in cell shape and cell motility in a living organism? We use Drosophila as a model system that allows combining genetics, live-imaging analyses with cell biological and biochemical approaches to identify and characterize regulatory components and signals controlling actin dynamics during development.

 

Membrane trafficking during sensory organ devleopment

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3D-reconstruction of sensory bristles (microchaetes) imaged from a thorax of a wild type pupa (40 APF). Green - socket cells, blue- neurons and red - bristle cells (F-actin).